Research

INTERNATIONAL COLLABORATION

Biomaterials for bone tissue engineering, improvement of biocompatibility and bioactivity by low temperature plasma treatment

NCBiR #PL-TWII/2015, „Polish-Taiwanese/Taiwanese-Polish Joint Research Call”

Hybrid growth factors delivery system supporting bone tissue regeneration

The main objective of the project is to develop a hybrid growth factors delivery system (HSDCW) for tissue engineering and regenerative medicine. The system will mimics the structure and function of the extracellular matrix (ECM) and delivers a controlled growth factors at the implantation site supporting the regeneration of bone tissue. HSDCW be formed from biodegradable polymeric nanofibres, which will contain both the bioceramic nanoparticles and at least two growth factors, for example: bone morphogenic protein – BMP and vascular endothelial growth factor (VEGF). Doses, kinetics of release and sequencing of release will be controlled by the construction of the nanofibers as well as the entire three-dimensional hybrid delivery system.

Duration: 13.12.2011 – 12.12.2015 (Harmonia NCN project # 2011/01/M/ST8/07742)

NanoBRIDGES – Marie Curie IRSES Action

The project is aimed at creating a worldwide network of research partnerships, including various types of research organizations from EU and third countries, with different profiles (computational and empirical risk assessors), focused on the development of new tools for computational risk assessment of engineered nanoparticles (NPs) http://nanobridges.eu/

New-joint

“Tissue engineering of osteochondral implants for joint repair”

Project proposal is related to the health area which is one of the targeted research priorities of the Polish-Norwegian Research Programme.
http://new-joint.pl/en

STEPS (FP6- MAT-IP)

A Systems Approach To Tissue Engineering Processes And Products.
Tasks:
– Fabrication of polymeric scaffold.
– Modifications of the scaffold surface.

COST MP0701

International project notfunded (Ministry / NCN) to COST Action MP0701 for 2010-2012.Project Title: Development of methods for producing three-dimensional composites with polymeric matrix modified with nanoparticles.Project manager: dr. Michael J. Wozniak. Grant amount: 1 670 000 PLN.

KMM-NoE (FP6- MAT-NoE)

Knowledge-Based Multicomponent Materials For Durable And Safe Performance:
– Testing and modeling of biomaterials.

CELLFORCE (FP6- IST&NMP-STREP) – CellForce:

Development of a single cell based biosensor for subcellular on-line monitoring of cell performance for diagnosis and healthcare.

Tasks:
– Design device for measure a forces in the cell.

MC EST: JOIN(ed)T (MC FP6)

Joined Education for Tissue Engineering: a multidisciplinary approach to regenerate joints
Task:
– Development of scaffold.

ExActResoMat (FP6 IP for SME)

External Activation of Resorbable Materials:
Tasks:
– Develop the method for external activation of implant   resorbtion.

COST533 (COST Action FP6)

Biotribology: Materials for improved wear resistance of total artificial joints:
Task:
– New materials for articular surfaces in Total Joint Replacement.
– Improvement properties of UHMWPE.
– Wear testing of the total joint replacement.

COST537 (COST Action FP6)

Core laboratories for the improvement of medical devices in clinical practice from the failure of the explanted prostheses analysis (FEPA):
Tasks:
– Analysis of the wear and degradation of biomaterials used in vivo.
– Study of the metallic parts: corrosion, fatigue, fracture.
– Non-distractive methods for retrievals analysis.

BIONANOCORE (Era Net Matera)

Bioactive Nanocomposite Constructs for Regeneration of Articular Cartilage:
Tasks:
– Cartilage Tissue Engineering.

RSHI-DLC-nanocomp (Era Net Matera)

Improvement of resurfacing hip implants with DLC, TiO2 and DLC-p-h nanocomposite coatings

Bilateral grant with Singapore

In vivo bone engineering via combining a novel composite scaffold technology with a growth factor potentiating collagen/heparan sulphate.

Plasma-­Bone‐BioMater

Biomaterials for Bone Tissue Engineering, Improvement of Biocompatibility and Bioactivity by Low Temperature Plasma Treatment. Project acronym: Plasma-Bone-BioMater. Polish-Taiwanese/Taiwanese-Polish Joint Research Call NCBR-MOST. 2015 – 2017.

AFM4NanoMed&Bio

Network on applications of Atomic Force Microscopy to NanoMedicine and Life Sciences COST Action TD1002 (AFM4NanoMed&Bio).

NATIONAL PROJECTS

DentalProt

“Biodegradable dental prosthesis, supporting preservation of the alveolar ridge after tooth extraction”

Grant: UMO-2011/01/B/ST8/07559 (OPUS, National Science Center of Poland)

“Three-dimensional composite scaffolds based on degradable polymers and bioceramics incorporated with the growth factors for bone tissue engineering”
Project Manager: Dr inż. Michał J. Woźniak
Funding: 999 800 PLN.

Project Iuventus Plus MNiSW

“Biomateriały kompozytowe polimer-ceramika, o strukturze naśladującej macierz pozakomórkową, dla potrzeb inżynierii tkankowej: procesy degradacji struktury i właściwości mechanicznych” Agreement: 0616/IP2/2011/71. Principal Investigator/Project Manager: Dr inż. Michał J. Woźniak. Funding: 154000 PLN.

Bio-Implant

Development and preparation of tissue engineering products which will support regeneration and restoration of large bone tissue loss http://bio-implant.pl.

PVA-Ti

In Vitro investigation of cartilage-like hydrogel materials and metallic porous structures for improvement of functionality of shoulder joint endoprostheses.

Coatings

Development of technology for coating the metallic implant with biocompatible polymeric layer playing a role of drug delivery system.

Porous Ti

Made by rapid prototyping method (in collaboration with Wroclaw University of Technology).

Mentor Eye

Opracowanie polskiego komplementarnego systemu molekularnej nawigacji chirurgicznej dla potrzeb leczenia nowotworów.

WIM-LKDIE

Zaawansowane techniki badań oddziaływań substancji czynnych z komórkami skóry w celu opracowania innowacyjnej receptury produktu kosmetycznego

NCN/Sonata

Zaawansowane techniki mikro i nano tomografii rentgenowskiej jako nowe narzędzie do badania i oceny produktów inżynierii tkankowej.

LasIMP

Innowacyjna technologia laserowego kształtowania przyrostowego LENS w zastosowaniu do modyfikacji geometrii i biofunkcjonalizacji warstwy powierzchniowej bezcementowych implantów stawu biodrowego